Abdullah Al Shamsh Prottay

Abdullah Al Shamsh Prottay

Biography

Abdullah Al Shamsh Prottay is an ardent pharmaceutical researcher specializing in pharmaceutical biotechnology, drug design, and in-vivo pharmacological studies. His research is dedicated to developing cost-effective therapeutic strategies from natural phytochemicals, with a strong focus on neurology and immunology. As an Associate Researcher at BioLuster Research Center Ltd. (BLRCL), Bangladesh, he plays a pivotal role in pioneering molecular docking, in-vivo behavioral models, and toxicity studies, striving to bridge the gap between cutting-edge science and real-world healthcare solutions.

With an unwavering commitment to advancing biomedical research, Abdullah is devoted to pushing the boundaries of pharmaceutical sciences and drug development. His relentless pursuit of knowledge and innovation drives him to explore novel therapeutic approaches that can redefine modern medicine. Looking ahead, he aspires to pursue a Master’s or Ph.D., further honing his expertise to make transformative contributions to biomedical innovation and global healthcare advancements.

 

Education

Abdullah completed his Bachelor of Pharmacy (B.Pharm) at Bangabandhu Sheikh Mujibur Rahman Science and Technology University (BSMRSTU), Gopalganj, Bangladesh. Throughout this rigorous four-year program, he gained extensive knowledge in Pharmacology, Medicinal chemistry, Biopharmaceutics, Pharmaceutical Technology, Clinical Pharmacy, Toxicology, and analytical techniques.

Before his university education, he consistently demonstrated academic excellence, achieving a GPA of 5.00 in both his Higher Secondary Certificate (HSC) (2015) and Secondary School Certificate (SSC) (2013) from Khulna Government Model School and College, Khulna, Bangladesh. His educational achievements reflect his dedication to research and innovation in pharmaceutical sciences.

 

In-Plant Training Program

General Production Facility, Renata Limited, Gazipur, Bangladesh

(30/07/2022 – 12/08/2022)

Website: https://renata-ltd.com/

  • Gained hands-on experience in maintaining and ensuring high standards in pharmaceutical manufacturing processes.
  • Understanding the theory and practical applications of various laboratory equipment, including HPLC, GC, pH Meter, Centrifuge, Tablet Hardness and Friability Testing Apparatus, Dissolution and Disintegration Tester.
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Research Focus & Expertise

Abdullah’s research lies at the intersection of neurology, immunology, and pharmaceutical biotechnology, with a focus on natural product-based drug discovery and targeted therapeutic strategies. He specializes in:

  • In-silico and molecular docking studies for the discovery of novel therapeutic compounds
  • Pharmacological evaluation of bioactive compounds using in-vivo behavioral models
  • Development of innovative therapeutic approaches for treating neurological and immunological disorders
  • Advanced bioinformatics and computational modeling to enhance drug design and research outcomes

His work aims to bridge the gap between cutting-edge science and practical, cost-effective treatments for improving public health.

 

Professional Experience

Associate Researcher

BioLuster Research Center Ltd., Bangladesh (January 2024 – Present)

  • Leading experimental research projects from initiation to data collection and analysis.
  • Guiding researchers in in-vivo behavioral models, molecular docking, and toxicity studies.
  • Ensuring ethical compliance in laboratory animal handling.
  • Promoting an innovative research environment in pharmaceutical sciences.

Research Assistant & Team Leader

Evergreen Scientific Research Centre, BSMRSTU (July 2020 – December 2023)

  • Supervised and mentored undergraduate students in Computer-Aided Drug Design (CADD).
  • Provided hands-on training in bioinformatics tools such as PyMOL, PyRx, Chem 3D Pro, and GaussView9 to enhance research accuracy.

Technical Skills

Computational Skills (Dry Lab Expertise)

  • Bioinformatics & Molecular Modeling: PyMOL / PyRx / AutoDock Vina / SPDBV /  UCSF ChimeraX / YASARA (Molecular Dynamics) / Chem 3D Pro / BioVia Discovery Studio Visualizer / ChemDraw Professional / MedChem Designer
  • Data Analysis: GraphPad Prism9 / SciDAVis / Endnote / Mendeley
  • Specialized Databases: PubChem / RCSB PDB / UniProt / ChemSpider / SWISS-MODEL / PDBsum / SwissADME / Deep-PK / ProTox-3.0

Laboratory Skills (Wet Lab Expertise)

  • Proficient in handling centrifuge machines, incubators, vortex mixers, electronic balances, and dissolution apparatus.
  • Experienced in animal model experiments for pharmacological research.

Computer literacy

  • Microsoft Windows / Microsoft Word / Microsoft PowerPoint / Microsoft Excel / Adobe Photoshop / Adobe Illustrator / Skype / Zoom / Google Docs / Email (Gmail)

 

Research Contributions & Conferences

International Conference Presentations

Bangladesh Council of Scientific and Industrial Research (BCSIR), Dhaka (March 2021)

  • Presented research titled "In-silico docking analysis of volasertib and its structural analogs against polo-like kinase (PLK1) for cancer treatment" (Abstract No: OP-D21).

 

Honors Research Project

Title: "Anti-inflammatory effects of sclareol possibly through COX inhibition pathway: In vivo and in silico study" (April 2020 – December 2020)

  • Investigated the biological activity of a labdane diterpenoid-based phytochemical.
  • Conducted in-vivo studies (formalin-induced paw edema model) in Swiss Albino mice.
  • Applied in-silico modeling to explore potential COX enzyme interactions.

 

Volunteering

Joint General Secretary, Pharmacy Association, BSMRSTU (10/04/2019 – 30/10/2022)

• Organized cultural programs and activities in the context of Career Advancement (For example: Workshops on how to write a research paper, Webinars for safe drug usage, CV building, etc.)

Activist, Blood Donating Organization (BADHAN) (07/02/2018 – Current)

• Conduct a free blood group analysis program and promote free blood donation.

Publications

 

Publications

  1. Prottay, A.A.S., Ripu, T.R., Sarwar, M.N., Rahman, T., Ahmmed, M.S., Bappi, M.H., Emon, M., Ansari, S.A., Coutinho, H.D. and Islam, M.T., 2025. Anxiogenic-like effects of coumarin, possibly through the GABAkine interaction pathway: Animal studies with in silico approaches. Behavioural Brain Research, 480, p.115392
  2. Islam, M.T., Prottay, A.A.S., Akbor, M.S., Bhuia, M.S., Islam, M.A. and Saifiuzzaman, M., 2024. Anxiolytic-like effect of daidzin possibly through GABAA receptor α2 and α3 subunits interaction pathway: In vivo and in silico studies. Pharmacological Research-Natural Products, 5, p.100090.
  3. Bappi, M.H., Mia, M.N., Ansari, S.A., Ansari, I.A., Prottay, A.A.S., Akbor, M.S., El‐Nashar, H.A., El‐Shazly, M., Mubarak, M.S. and Torequl Islam, M., 2024. Quercetin increases the antidepressant‐like effects of sclareol and antagonizes diazepam in thiopental sodium‐induced sleeping mice: a possible GABAergic transmission intervention. Phytotherapy Research, 38(5), pp.2198-2214.
  4. Prottay, A.A.S., Bappi, M.H., Akbor, M.S., Asha, A.I., Bhuia, M.S., Shafin, A.A., Mia, M.N., Mubarak, M.S., de Azevedo Lima, M., Coutinho, H.D.M. and Islam, M.T., 2024. Sclareol exerts an anti-inflammatory effect, possibly through COXs inhibition pathway: In vivo and in silico studies. Pharmaceutical Science Advances, 2, p.100029.
  5. Akbor, M.S., Bappi, M.H., Prottay, A.A.S., Haque, M.F., Al Hasan, M.S., Ahammed, S., Chowdhury, R.I., Hosain, M.S., Lima, C.M.G., Ahmad, S.F. and Attia, S.M., 2023. Synergistic hypnotic effects of sesamol and thymol possibly through GABAergic interaction pathway: in vivo and in silico studies. J. Biol. Regul. Homeost. Agents, 37(11), pp.6419-6435.
  6. Kamli, H., Shaikh, A., Bappi, M.H., Raposo, A., Ahmad, M.F., Sonia, F.A., Akbor, M.S., Prottay, A.A.S., Gonçalves, S.A., Araújo, I.M. and Coutinho, H.D.M., 2023. Sclareol exerts synergistic antidepressant effects with quercetin and caffeine, possibly suppressing GABAergic transmission in chicks. Biomedicine & Pharmacotherapy, 168, p.115768.
  7. Bappi, M.H., Prottay, A.A.S., Al-Khafaji, K., Akbor, M.S., Hossain, M.K., Islam, M.S., Asha, A.I., Medeiros, C.R., Tahim, C.M., Lucetti, E.C.P. and Coutinho, H.D.M., 2023. Antiemetic effects of sclareol, possibly through 5-HT3 and D2 receptor interaction pathways: in-vivo and in-silico studies. Food and Chemical Toxicology, 181, p.114068.
  8. Islam, M.T., Bappi, M.H., Islam, T., Prottay, A.A.S., Akbor, S. and Mia, N., 2023. Toxicology of rabeprazole: a literature survey and an in silico study. Kariri Science-CECAPE Biology and Health Journal, 1(1), pp.1-6.
  9. Mia, M.A.R., Dey, D., Sakib, M.R., Biswas, M.Y., Prottay, A.A.S., Paul, N., Rimti, F.H., Abdullah, Y., Biswas, P., Iftehimul, M. and Paul, P., 2023. The efficacy of natural bioactive compounds against prostate cancer: Molecular targets and synergistic activities. Phytotherapy Research, 37(12), pp.5724-5754.
  10. Mia, M.N., Smrity, S.Z., Bappi, M.H., Kamli, H., Islam, T., Prottay, A.A.S., Akbor, M.S., Latif, M.A., Islam, S., Bhakta, K. and Shill, M.C., 2023. Anxiolytic-like effect of succinic acid: a possible GABAergic intervention. Food Bioscience, 55, p.103044.
  11. Bappi, M.H., Prottay, A.A.S., Kamli, H., Sonia, F.A., Mia, M.N., Akbor, M.S., Hossen, M.M., Awadallah, S., Mubarak, M.S. and Islam, M.T., 2023. Quercetin antagonizes the sedative effects of linalool, possibly through the GABAergic interaction pathway. Molecules, 28(14), p.5616.
  12. Islam, M., Prottay, A.A.S., Sultana, I., Al Faruq, A., Bappi, M.H., Akbor, M.S., Asha, A.I., Hossen, M.M., Machado, P.E.M., Junior, I.J.S. and Coutinho, H.D.M., 2023. Phytochemical screening and evaluation of antioxidant, anti-inflammatory, antimicrobial, and membrane-stabilizing activities of different fractional extracts of Grewia nervosa (Lour.) Panigrahi. Food Bioscience, 54, p.102933.
  13. Jannah, M.H., Prottay, A.A.S., Chowdhury, M.M., Ahmed, M.B., Chowdhury, M.M.U. and Islam, M.T., 2023. PRELIMINARY PHYTOCHEMICAL SCREENING AND BIOACTIVITY INVESTIGATIONS OF AVORRHEA CARAMBOLA L. Khulna University Studies, pp.49-61.
  14. Bhuia, M.S., Rahaman, M.M., Islam, T., Bappi, M.H., Sikder, M.I., Hossain, K.N., Akter, F., Al Shamsh Prottay, A., Rokonuzzman, M., Gürer, E.S. and Calina, D., 2023. Neurobiological effects of gallic acid: Current perspectives. Chinese Medicine, 18(1), p.27.
  15. Bhuia, M.S., Islam, T., Rokonuzzman, M., Shamsh Prottay, A.A., Akter, F., Hossain, M.I., Chowdhury, R., Kazi, M.A., Khalipha, A.B.R., Coutinho, H.D.M. and Islam, M.T., 2023. Modulatory effects of phytol on the antiemetic property of domperidone, possibly through the D2 receptor interaction pathway: in vivo and in silico studies. 3 Biotech 13 (4): 116 
  16. Khalipha, A.B.R., Hossain, M.S., Prottay, A.A.S. and Sakib, M.R., 2019. Mini-review of Litsea glutinosa and molecular docking studies of boldine (derived from Litsea glutinosa) and its derivatives for anticancer activity against TNFRSF6B. Int. J. Evergr. Sci. Res, 3, pp.1-20.
  17. Prottay, A.A.S., Khalipha, A.B.R., Sakib, M.R., Sarkar, C. and Bagchi, R., 2019. DISCOVERY OF FEDRATINIB DERIVATIVES TARGETING JANUS KINASE 2 (JAK2): AN IN-SILICO STUDY.
  18. Haque, M.I., Khalipha, A.B.R., Sakib, M.R., Prottay, A.A.S., Islam, M.A., Zannat, R., Sardar, S. and Santa, N.Z., 2021. In-silico molecular docking study of linalool against 3ELJ for cell cycle arrest and apoptosis in HepG2 cells. International Journal of Evergreen Scientific Research Research Paper, 3(2), p.105.

  19. Rahaman, M.M., Ahmed, R., Prottay, A.A.S., Hossain, M.N. and Islam, M.T., 2017. Ethnopharmacology, phytochemistry, and pharmacology of Uvaria acuminata Oliv. Int J Adv Biochem Res, 1, pp.43-46.

 

Contact

 

Email: abdullah103637@gmail.com