Rubel Hasan

Rubel Hasan

Biography

 

Rubel Hasan is a dedicated researcher in pharmacy and other relevant biological fields. He has done both his Bachelor’s (B.Pharm) and Master’s (M.Pharm) degrees in pharmacy under life science faculty at Bangabandhu Sheikh Mujibur Rahman Science and Technology University, Gopalganj 8100 (BSMRSTU), Bangladesh. Currently, he is the Principal Investigator at BioLuster Research Center Ltd (BLRCL), where he leads pioneering research projects aimed at advancing biomedical science. He is mainly interested in neurology, immunology, cancer, computational studies, natural products, and preclinical evaluation of toxicology. However, currently, he is seeking a PhD opportunity in his relevant field. Rubel Hasan is committed to making impactful contributions in the medical research field.

Education

 

Rubel Hasan is a passionate researcher in the field of pharmacy, with a strong focus on advancing healthcare through scientific research. He achieved his graduation (B.Pharm) and post-graduation (M.Pharm) degrees from the Department of Pharmacy under the Faculty of Life Sciences at BSMRSTU, Gopalganj 8100, Bangladesh. The B.Pharm degree lasted four years and eight semesters; on the other hand, the M.Pharm degree ended in two semesters over a period of one year.

In his B.Pharm degree, he successfully completed his project work on drug design and exploration with the title  “Antiemetic Activity of Abietic Acid Possibly through the 5HT3 and Muscarinic Receptor Interaction Pathways’’ under the supervision of Associate Professor Dr. Muhammad Ali Khan. Before starting university studies, he completed his Higher Secondary Certificate (HSC) examination under the Science Group at Jamalpur Residential Model College, Jamalpur, and Secondary School Certificate (SSC) examination under the Science Group at Sanandabari High School, Jamalpur, Dewanganj.

Experience

 

Active Researcher 

BioLuster Research Ltd, Gopalganj 8100, Dhaka

Role: Associate Investigator

Active: December 2023-Present

Responsibilities Include: 

  • Study design
  • Developing new methods
  • Supervising project students
  • Evaluation of review and research manuscripts
  • Lab investigation (Conduction of in silico and animal experiments)
  • Conducting classes for students and junior researchers

B. Pharm Project work

Department of Pharmacy, Life Science Faculty

Bangabandhu Sheikh Mujibur Rahman Science and Technology University

Project title: Antiemetic Activity of Abietic Acid Possibly through the 5HT3 and Muscarinic Receptors Interaction Pathways

Supervisor: Dr. Muhammad Ali Khan

Responsibilities Include: 

  • Existing literature review for identifying the biological activity of the natural compound (abietic acid)

  • Identification of toxicity range of abietic acid using Allium Cepa brine shrimp model

  • Preclinical study of natural compound (abietic acid) on biological activity in experimental animals 

  • Evaluation of antiemetic activity on chicks

  • Investigation of other biological activities (Anti-inflammatory, antidiarrheal)

  • Molecular docking and dynamic simulation of ligand-receptor interaction to assess the molecular interaction

  • Assessment of in silico pharmacokinetics and toxicity using various computational tools

Academic Skill

 

Molecular Docking | Homology Modeling | In-silico ADMET Analysis | In silico Drug Design | Autoclave Machine | Microorganism Culture | Culture and Characterization of Microorganisms | DNA Isolation | TLC| Polarimeter | Colorimeter | Handling Laboratory Animals | Drawing of Chemical Structures | Serological and Hematological Tests of Blood | Chemical Group Identification | Preclinical Tests on Laboratory Animals | Acid-Base Titration | Solid Phase Extraction | Validation | Plant’s Compound extraction | Toxicity Analysis via A. cepa Bio-model | Molecular Mechanisms of Pharmacological Action | Pharmacological Evaluation | Antioxidant Biology | Literature Review | Phytochemical Profiling and Evaluation of Bioactivities.

Publications

 

  1. Hasan, R., Alshammari, A., Albekairi, N. A., Bhuia, M. S., Afroz, M., Chowdhury, R., Khan, M. A., Ansari, S. A., Ansari, I. A., Mubarak, M. S., & Islam, M. T. (2024). Antiemetic activity of abietic acid possibly through the 5HT3 and muscarinic receptors interaction pathways. Scientific reports, 14(1), 6642. https://doi.org/10.1038/s41598-024-57173-0 (Q1, IF: 4.6)
  2. Hasan, R., Bhuia, M. S., Chowdhury, R., Saha, S., Khan, M. A., Afroz, M., Ansari, S. A., Ansari, I. A., Melo Coutinho, H. D., & Islam, M. T. (2024). Abietic acid antagonizes the anti-inflammatory effects of celecoxib and ketoprofen: Preclinical assessment and molecular dynamic simulations. Computers in biology and medicine, 183, 109298. Advance online publication. https://doi.org/10.1016/j.compbiomed.2024.109298 (Q1, IF:7.7, CS:11.7) 
  3. Hasan, R., Bhuia, M. S., Chowdhury, R., Khan, M. A., Mazumder, M., Yana, N. T., Alencar, M. V. O. B., Ansari, S. A., Ansari, I. A., & Islam, M. T. (2024). Piperine exerts anti-inflammatory effects and antagonizes the properties of celecoxib and ketoprofen: in vivo and molecular docking studies. Natural product research, 1–16. Advance online publication. https://doi.org/10.1080/14786419.2024.2413039 (Q1, IF:1.9, CS: 5.9)
  4. Afroz, M., Bhuia, M.S., Rahman, M.A., Hasan, R., Islam, T., Islam, M.R., Chowdhury, R., Khan, M.A., e Silva, D.A., Coutinho, H.D.M., & Islam, M.T. (2023). Anti-diarrheal effect of piperine possibly through the interaction with inflammation inducing enzymes: In vivo and in silico studies. European Journal of Pharmacology, 176289. https://doi.org/10.1016/j.ejphar.2023.176289  (Q1, IF: 5, CS: 8.7)
  5. Chowdhury, R.; Bhuia, M.S.; Rakib, A.I.; Hasan, R.; Coutinho, H.D.M.; Araújo, I.M.; de Menezes, I.R.A.; Islam, M.T. (2023). Assessment of Quercetin Antiemetic Properties: In Vivo and In Silico Investigations on Receptor Binding Affinity and Synergistic Effects. Plants 2023, 12, 4189. https://doi.org/10.3390/plants12244189  (Q1, IF: 4.5)
  6. Mukty, S. A., Hasan, R., Bhuia, M. S., Saha, A. K., Rahman, U. S., Khatun, M. M., Bithi, S. A., Ansari, S. A., Ansari, I. A., & Islam, M. T. (2024). Assessment of sedative activity of fraxin: In vivo approach along with receptor binding affinity and molecular interaction with GABAergic system. Drug development research, 85(6), e22250. https://doi.org/10.1002/ddr.22250 (Q2, IF: 3.5, CS: 5.2)
  7. Islam, M. T., Bhuia, M. S., Sheikh, S., Hasan, R., Bappi, M. H., Chowdhury, R., Ansari, S. A., Islam, M. A., & Saifuzzaman, M. (2024). Sedative Effects of Daidzin, Possibly Through the GABAA Receptor Interaction Pathway: In Vivo Approach with Molecular Dynamic Simulations. Journal of molecular neuroscience: MN, 74(3), 83. https://doi.org/10.1007/s12031-024-02261-z (IF: 2.8)
  8. Disha, I. J., Hasan, R., Bhuia, S., Ansari, S. A., Ansari, I. A., & Islam, M. T. (2024). Anxiolytic Efficacy of Indirubin: In Vivo Approach Along with Receptor Binding Profiling and Molecular Interaction with GABAergic Pathways. ChemistryOpen, e202400290. Advance online publication. https://doi.org/10.1002/open.202400290 (IF:2.5, CS:4.8)
  9. Chowdhury, R., Bhuia, M. S., Wilairatana, P., Afroz, M., Hasan, R., Ferdous, J., Rakib, A. I., Sheikh, S., Mubarak, M. S., & Islam, M. T. (2024). An insight into the anticancer potentials of lignan arctiin: A comprehensive review of molecular mechanisms. Heliyon, 10(12), e32899. https://doi.org/10.1016/j.heliyon.2024.e32899 (Q1, IF: 3.4, CS: 4.5)
  10. Aktar, M. A., Bhuia, M. S., Chowdhury, R., Hasan, R., Rakib, A. I., Al Hasan, M. S., Sonia, F. A., & Islam, M. T. (2024). Therapeutic Promises of Bioactive Rosavin: A Comprehensive Review with Mechanistic Insight. Chemistry & biodiversity, e202400286. Advance online publication. https://doi.org/10.1002/cbdv.202400286. (Q2, IF: 2.74)
  11. Aktar, M. A., Bhuia, M. S., Chowdhury, R., Ferdous, J., Khatun, M. M., Al Hasan, M. S., Mia, E., Hasan, R., & Islam, M. T. (2024). An Insight of Plant Source, Toxicological Profile, and Pharmacological Activities of Iridoid Loganic Acid: A Comprehensive Review. Chemistry & biodiversity, e202400874. Advance online publication. https://doi.org/10.1002/cbdv.202400874 (Q2, IF: 2.74)

Hobby

Research Article Writing II Reading Book

Contact

 

 Phone number: +8801781175482

  Email: rubelhasanphr2@gmail.com

  Whatsapp: +8801781175482